Recombinant Human CXCL11

Catalog No : IGX-RP590
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Product name Recombinant Human CXCL11
Catalog No IGX-RP590
Supplier’s Catalog No IGX-RP590
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 8
Storage -70°C
Other names CXCL11, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11<br/>Recombinant Human IFN-Inducible T-cell Chemoattractant (CXCL11)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PB,100 mM NaCl pH 7.5
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description The CXCL11 belongs to the CXC chemokine family characterized by the presence of one amino acid in between the two NH2-terminal cysteines. CXCL11 is produced by a variety of cells including leukocytes, fibroblasts, and endothelial cells upon stimulation with interferons (IFNs). Simultaneous stimulation of fibroblasts or endothelial cells with IFN-gamma and Interleukin-1b or the TLR3 ligand double-stranded RNA results in a synergistic increase of CXCL11 production. CXCL11 attracts natural killer cells and activated T-helper 1 cells. Like CXCL9 and CXCL10, CXCL11 signals through CXC chemokine receptor 3 (CXCR3).