Recombinant Human FGF10

Catalog No : IGX-RP596
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Product name Recombinant Human FGF10
Catalog No IGX-RP596
Supplier’s Catalog No IGX-RP596
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 19
Storage -70°C
Other names FGF-10, FGFA, Keratinocyte growth factor-2<br/>Recombinant Human Fibroblast Growth Factor 10 (FGF10)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from 0.2 μm filtered solution in PBS (pH 7.0) and 1mM DTT
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description FGF-10 is involved in the initial budding as well as the continuous outgrowth of vertebrate limbs. FGF-10 mRNA is expressed preferentially in neurons but not in glial cells and may have a distinct role in the brain. Human FGF-10 is mitogenic for fetal rat keratinizing epidermal cells but not for NIH 3T3 cells. Recombinant FGF-10 induces the proliferation of human urothelial cells in vitro and induces the proliferation of transitional epithelium. FGF-10 is secreted by cultured mouse pre- adipocytes, prevention of FGF-10 signaling inhibits subsequent differentiation. The ability of embryonic fibroblasts derived from FGF-10 knock-out mice to differentiate into adipocytes is also impaired.