Recombinant Human IFNA1 (IFN-alpha1)

Catalog No : IGX-RP613
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Product name Recombinant Human IFNA1 (IFN-alpha1)
Catalog No IGX-RP613
Supplier’s Catalog No IGX-RP613
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 19.7
Storage -70°C
Other names Interferon alpha-D, IFN-alpha-1/13, LeIF D, IFNA13
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in Tris and NaCl (pH 8.0)
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description All known subtypes of IFN- alpha show the same antiviral antiparasitic, antiproliferative activities. IFN-alpha forms are produced by monocytes/macrophages, lymphoblastoid cells, fibroblasts, and a number of different cell types following induction by viruses, nucleic acids, glucocorticoid hormones, and low-molecular weight substances. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. IFN-alpha and IFN-beta are thought to bind to the same receptor. Signal transduction mechanisms elicited after binding of IFN-alpha to its receptors involves tyrosine phosphorylation of various non-receptor tyrosine kinases belonging to the Janus kinases.