Recombinant Human KGF (FGF7)

Catalog No : IGX-RP638
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Product name Recombinant Human KGF (FGF7)
Catalog No IGX-RP638
Supplier’s Catalog No IGX-RP638
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 19
Storage -70°C
Other names KGF, Fibroblast Growth Factor-7, HBGF-7, Heparin-binding growth factor 7<br/>Recombinant Human Keratinocyte Growth Factor (FGF7)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PBS (pH 7.0)
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description KGF is a member of the family of fibroblast growth factors, it is secreted in large amounts by fibroblast-like stromal cells in epithelial tissues. The KGF receptor encodes a tyrosine kinase and is a member of the family of receptors binding aFGF and bFGF. Binding of KGF to its receptor is competed by aFGF and bFGF. Although KGF is a potent specific mitogen for many epithelial cells it is not so for fibroblasts and endothelial cells. KGF is thought to play an important role in the paracrine growth control of normal epithelial cells. KGF stimulates the proliferation of primary and secondary human keratinocytes to the same extent as EGF.