Recombinant Human LIF

Catalog No : IGX-RP639
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Product name Recombinant Human LIF
Catalog No IGX-RP639
Supplier’s Catalog No IGX-RP639
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 20
Storage -70°C
Other names LIF, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor (MLPLI) <br/>Recombinant Human Leukemia Inhibitory Factor (LIF)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered PBS pH 7.0
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.