Recombinant Human MANF

Catalog No : IGX-RP640
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Product name Recombinant Human MANF
Catalog No IGX-RP640
Supplier’s Catalog No IGX-RP640
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 18.4
Storage -70°C
Other names Arginine-rich protein, Protein ARMET, ARP<br/>Recombinant Human Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PBS
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description MANF is a neurotrophic factor found mainly in central nervous tissues where it may remain localized to the endoplasmic reticulum/Golgi apparatus, or secreted. It has been shown that MANF plays an important role in protecting cells against tunicamycin and thapsigargin -induced cell death. Without MANF, cells become increasingly vulnerable to the aforementioned drugs. Also, MANF is structurally homologous to CDNF.