Recombinant Human MIF

Catalog No : IGX-RP643
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Product name Recombinant Human MIF
Catalog No IGX-RP643
Supplier’s Catalog No IGX-RP643
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 15
Storage -70°C
Other names Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, EC=5.3.3.12, Phenylpyruvate tautomerase, GLIF, MMIF, MIF<br/>Recombinant Human Macrophage Migration Inhibitory Factor (MIF)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Recombinant human MIF was lyophilized from a 0.2 μm filtered solution PBS pH 7.4
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description Macrophage Migration Inhibitory Factor (MIF) is a proinflammatory cytokine. MIF is involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.