Recombinant Human TNF
Catalog No : IGX-RP654
211.59€
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| Product name | Recombinant Human TNF | ||
|---|---|---|---|
| Catalog No | IGX-RP654 | ||
| Supplier’s Catalog No | IGX-RP654 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 17.6 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin<br/>Recombinant Human Tumor Necrosis Factor Alpha (TNF) | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered solution in PBS (pH 7.2) | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | Tumor Necrosis Factor is secreted by macrophages, monocytes, neutrophils, T cells, natural killer cells following their stimulation by bacterial lipopolysaccharides although cells expressing CD8(+) secrete little or no TNF-alpha. In addition, TNF is secreted by peripheral neutrophilic granulocytes and by a number of transformed cell lines that include those of astrocytes, microglial cells, smooth muscle cells and fibroblasts. Human milk also contains this factor. The synthesis of TNF-alpha is induced by many different stimuli including interferons, IL2, GM-CSF, SP, Bradykinin, Immune complexes, inhibitors of cyclooxygenase and platelet activating factor. TNF-alpha shares approximately 30% homology with TNF-beta. Human TNF-alpha is a non-glycosylated protein of 17.6 kDa. | ||
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