Imugex

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Categories: Peptides & Proteins / Proteins

Storage			-70°C
Other names			IL-6, B-cell hybridoma growth factor, Interleukin HP-1<br/>Recombinant Mouse Interleukin-6 (IL6)
Grade			Highly Purified
Purity			>95% as determined by SDS-PAGE
Form			Lyophilized from a 0.2 μm filtered solution in PBS
Reactivity life			6 months
Note			For reserch purpose only
Purity			>95% as determined by SDS-PAGE
Description			IL6 is produced by many different cell types. The main sources in vivo are stimulated monocytes, fibroblasts, and endothelial cells. Macrophages, T cells and B-lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells, and keratinocytes also produce IL6 after stimulation. IL6 is a member of a family of cytokines, which also includes LIF, CNTF, Oncostatin M, IL11, and CT-1. All known members of the IL6 cytokine family induce hepatic expression of acute phase proteins. The IL6 receptor is expressed on T cells, mitogen-activated B cells, peripheral monocytes and some macrophage and B cell derived tumor cell types. It is not expressed in resting B cells but in resting T cells. The IL6 receptor, designated CD126, is a strongly glycosylated protein of 80 kDa. Recombinant Mouse IL6 is a 22 kDa polypepdtide with two intramolecular disulfide bridges.