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Categories: Peptides & Proteins / Proteins

Product name			Recombinant Mouse Stem Cell Factor (KITLG)
Catalog No			IGX-RP671
Supplier’s Catalog No			IGX-RP671
Supplier			ImuGeX
Source antigen			E. coli
Reactivity			Mouse
Cross reactivity
Applications
Molecular weight			18.9

Storage			-70°C
Other names			SCF, Kit ligand, c-Kit ligand, Hematopoietic growth factor KL, Mast cell growth factor, MGF, Steel factor
Grade			Highly Purified
Purity			>95% as determined by SDS-PAGE
Form			Lyophilized from a 0.2 μm filtered solution in Tris and NaCl (pH 8.0)
Reactivity life			6 months
Note			For reserch purpose only
Purity			>95% as determined by SDS-PAGE
Description			SCF is a stromal cell-derived cytokine synthesized by fibroblasts and other cell types. SCF promotes proliferation and early differentiation of cells at the level of multipotential stem cells. It has been suggested that SCF is essential for optimal production of various hematopoietic lineages. The receptor for SCF, designated SCFR (CD117), is the oncogene designated as KIT. The biological activities of SCF are synergised considerably by GM-CSF and G-CSF, and also by IL7, EPO and some other growth and differentiation factors. In combination with IL7, SCF stimulates the proliferation of pre-B cells. SCF is also a potent chemoattractant for cells, such as mast cells, expressing the KIT receptor.