Recombinant Human CXCL1

Catalog No : IGX-RP697
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Product name Recombinant Human CXCL1
Catalog No IGX-RP697
Supplier’s Catalog No IGX-RP697
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 8
Storage -70°C
Other names Growth Regulated Protein, Melanoma Growth Stimulatory Activity, GRO-alpha, MGSA-alpha, CXCL1, NAP-3, GRO1, C-X-C motif chemokine 1, GRO-alpha(1-73)<br/>Recombinant Human Growth Regulated Alpha Protein (CXCL1)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in 40 mM NaCl and PB, pH 7.0
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description A chemokine, the growth regulated oncogene-alpha is identical with MGSA (melanoma growth stimulatory activity) with its new designation being CXCL1. The expression of GRO can be induced by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B.