Recombinant Human ABL2 (N-His tag)
Catalog No : IGX-RP699
366.40€
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| Product name | Recombinant Human ABL2 (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP699 | ||
| Supplier’s Catalog No | IGX-RP699 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 132 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | ARG; ABLL | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | ABL2 (or ARG) is a nonreceptor cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of ABL1 and ABL2 includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is involved in translocation with the ETV6 gene in human leukemia and has an altered expression in several human carcinomas . Two isoforms of ABL2 with different N-termini (1A and 1B) have been identified. The C-terminal domain of ABL2 contains two F-actin-binding sequences that perform a number of actions related to cell morphology and motility by interacting with actin filaments . | ||
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