Recombinant Human AKT2 (N-His tag)

Catalog No : IGX-RP703
366.40€
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Product name Recombinant Human AKT2 (N-His tag)
Catalog No IGX-RP703
Supplier’s Catalog No IGX-RP703
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 58
Storage -70°C
Other names PRKBB; PKBBETA; RAC-BETA
Grade Highly Purified
Purity 70% - 90%
Form 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description AKT2 or Protein Kinase B ß (PKBß) is a serine/threonine kinase that is a member of the AKT family. AKT2 like the other AKT members is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix components and is involved in glucose metabolism, transcription, survival, cell proliferation, angiogenesis, and cell motility. The PI3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP3), a lipid second messenger essential for the translocation of AKT2 to the plasma membrane where it is phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1).