Recombinant Human ALK (N-GST tag)
Catalog No : IGX-RP705
366.40€
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| Product name | Recombinant Human ALK (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP705 | ||
| Supplier’s Catalog No | IGX-RP705 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 90 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | ALK (Ki-1), CD246, NBLST3, TFG/ALK | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | Â ALK or anaplastic lymphoma kinase is a receptor tyrosine kinase that was originally identified as a member of the insulin receptor subfamily that acquires transforming capability when truncated and fused to NPM (nucleophosmin) in the t(2;5) chromosomal rearrangement associated with ALCL Many chromosomal rearrangements leading to enhanced ALK activity have been described and are implicated in a number of cancer types . In the nervous system, ALK in the presence of ligand appears essential for axonal guidance, whereas in the absence of ligand, ALK expression can lead to developmental neuronal apoptosis . | ||
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