Recombinant Human ALK3 (BMPR1A) (N-GST tag)

Catalog No : IGX-RP708
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Product name Recombinant Human ALK3 (BMPR1A) (N-GST tag)
Catalog No IGX-RP708
Supplier’s Catalog No IGX-RP708
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 66
Storage -70°C
Other names ALK3; BMPR1A; 10q23del; ACVRLK3; CD292; SKR5
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description  BMPR1A (also known as bone morphogenetic protein receptor 1A) is a member of the transmembrane serine/threonine kinase family that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A act as a minor susceptibility gene for PTEN-mutation-negative Cowden syndrome. BMPR1A regulates the PTEN protein levels by decreasing PTEN's association with the degradative pathway . BMPR1A trafficking plays a significant role in FOP pathogenesis and is also involved in human T-cell differentiation .