Recombinant Human AMPK (A1/B1/G1) (C-His tag)

Catalog No : IGX-RP711
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Product name Recombinant Human AMPK (A1/B1/G1) (C-His tag)
Catalog No IGX-RP711
Supplier’s Catalog No IGX-RP711
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 68
Storage -70°C
Other names Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G1: PRKAG1, AMPKG, MGC8666
Grade Highly Purified
Purity 70% - 90%
Form 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description AMPK is a heterotrimer protein kinase consisting of an a catalytic subunit, and non-catalytic ß and ? subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status . In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol .