Recombinant Human AMPK (A1/B1/G2) (C-His tag)
Catalog No : IGX-RP713
617.44€
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Product name | Recombinant Human AMPK (A1/B1/G2) (C-His tag) | ||
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Catalog No | IGX-RP713 | ||
Supplier’s Catalog No | IGX-RP713 | ||
Supplier | ImuGeX | ||
Source antigen | Insect cells | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 68 |
Storage | -70°C | ||
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Other names | Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G2: PRKAG2, AAKG, CMH6, WPWS, AAKG2, H91620p | ||
Grade | Highly Purified | ||
Purity | 70% - 90% | ||
Form | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | 70% - 90% | ||
Description | AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis . AMPK exists as a heterotrimeric complex composed of a catalytic a subunit and regulatory ß and ? subunits. Binding of AMP to the ? subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia) and via signaling pathways in response to adiponectin, leptin and CAMKKß. |
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