Recombinant Human AMPK (A1/B2/G1) (C-His tag)

Catalog No : IGX-RP717
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Product name Recombinant Human AMPK (A1/B2/G1) (C-His tag)
Catalog No IGX-RP717
Supplier’s Catalog No IGX-RP717
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 68
Storage -70°C
Other names Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B2: PRKAB2, MGC61468 Subunit G1: PRKAG1, AMPKG, MGC8666
Grade Highly Purified
Purity 70% - 90%
Form 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description AMPK (A1/B2/G1) is a member of the AMPK family which are heterotrimeric proteins consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress . AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and hydroxy beta-methylglutaryl-CoA reductase. The ß subunit may be a positive regulator of AMPK activity and is highly expressed in skeletal muscle .