Recombinant Human AURORA C (N-GST tag)
Catalog No : IGX-RP732
366.40€
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| Product name | Recombinant Human AURORA C (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP732 | ||
| Supplier’s Catalog No | IGX-RP732 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 61 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | AURKC, AIE2, AIK3, AurC, STK13, aurora-C | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | Aurora C is a member of mitotic serine/threonine kinases that regulate centrosome maturation, chromosome segregation, and cytokinesis. Aurora C has been shown to contribute to oncogenic transformation and is frequently overexpressed and amplified in many human tumors . Aurora C overexpression has been correlated with centrosome amplification, which can be a driving cause of genomic instability in tumor cells. Aurora C is an important regulator of both genomic integrity and cell cycle progression in cancer cells and is an attractive target for anticancer drug development . | ||
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