Recombinant Human CAMK2 alpha (N-GST tag)

Catalog No : IGX-RP748
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Product name Recombinant Human CAMK2 alpha (N-GST tag)
Catalog No IGX-RP748
Supplier’s Catalog No IGX-RP748
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 74
Storage -70°C
Other names CAMKA; KIAA0968
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description CAMK2a is a ser/thr protein kinase that is a member of the Ca2+/calmodulin-dependent protein kinase family. CAMK2a is abundant in the brain as a major constituent of the postsynaptic density and is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its Ca2+/calmodulin-dependent activity, CAMK2a can undergo autophosphorylation, resulting in Ca2+/calmodulin-independent activity. The protein level of CAMK2a fluctuates during neuronal activity in cultured rat pup hippocampal neurons. The levels of CAMK2a increased with heightened neuronal activity .Â