Recombinant Human CDK3/CyclinE1 (N-GST tag)

Catalog No : IGX-RP767
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Product name Recombinant Human CDK3/CyclinE1 (N-GST tag)
Catalog No IGX-RP767
Supplier’s Catalog No IGX-RP767
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 60
Storage -70°C
Other names CDK3: None CyclinE1: CCNE1, CCNE
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description CDK3/CyclinE1is a member of the cyclin-dependent protein kinase family and promotes entry into S phase, in part by activating members of the E2F family of transcription factors. CDK3 can also associate with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. The CDK3 gene has been mapped to chromosomal location of 17q22-qter, telomeric to the BRCA1 gene by somatic cell hybrids analysis . The presence of a single point mutation in the CDK3 gene from several Mus musculus strains commonly used in the laboratory has been reported .