Recombinant Human CDK9/CyclinK (N-GST tag)
Catalog No : IGX-RP775
366.40€
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| Product name | Recombinant Human CDK9/CyclinK (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP775 | ||
| Supplier’s Catalog No | IGX-RP775 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 68 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | CDC2L4, C-2k, TAK, PITALRE; CCNK, CPR4, MGC9113 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | CDK9/CyclinK is a member of the cyclin-dependent protein kinase (CDK) family. CDK9 is closely related to cdc28 and cdc2 and is an important regulator of the cell cycle . CDK9 is a component of the multiprotein complex TAK/P-TEFß. CDK9 can modulate RNA polymerase II-directed transcription by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. CDK9 forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. CDK9 also interacts with the HIV-1 Tat protein which suggested a possible involvement of this protein in AIDS . | ||
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