Recombinant Human CLK4 (N-GST tag)

Catalog No : IGX-RP792
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Product name Recombinant Human CLK4 (N-GST tag)
Catalog No IGX-RP792
Supplier’s Catalog No IGX-RP792
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 73
Storage -70°C
Other names DKFZp686A20267
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description CLK4 or CDC-like kinase 4 belongs to the CDC2-like protein kinase (CLK) family that can interact with and phosphorylate the serine- and arginine-rich (SR) proteins. The SR proteins are known to play an important role in the formation of spliceosomes and thus may be involved in the regulation of alternative splicing. CLK4 expressed in E. coli phosphorylated myelin basic protein as a substrate as well as autophosphorylating itself but it did not phosphorylate H2B .