Recombinant Human DAPK1 (N-GST tag)
Catalog No : IGX-RP796
366.40€
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| Product name | Recombinant Human DAPK1 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP796 | ||
| Supplier’s Catalog No | IGX-RP796 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 71 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | DAPK, DKFZp781I035 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | Death-associated protein kinase 1 (DAPK1) is a positive mediator of apoptosis induced by ?-interferon. Activation of DAPK occurs via dephosphorylation of Ser-308 and subsequent association of calcium/calmodulin . DAPK is rapidly dephosphorylated in response to tumor necrosis factor or ceramide and then subsequently degraded via proteasome activity. The decline in DAPK expression is paralleled with increased caspase activity and cell apoptosis. Studies suggest that the apoptosis regulatory activities mediated by DAPK are controlled both by phosphorylation status and protein stability . | ||
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