Recombinant Human DMPK (N-GST tag)
Catalog No : IGX-RP803
366.40€
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| Product name | Recombinant Human DMPK (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP803 | ||
| Supplier’s Catalog No | IGX-RP803 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 105 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | DM, DM1, DMK, MDPK, DM1PK, MT-PK | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | DMPK (or Myotonic Dystrophy Protein Kinase) is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. DMPK protein has a leucine-rich domain at the N-terminus, a serine/threonine kinase domain in the middle, and a hydrophobic region at the C-terminus. The N-terminus of DMPK plays an important role in DMPK kinase activity, and the C-terminus of DMPK determines the intracellular localization of the protein . Myotonic dystrophy type 1 is an autosomal dominant disease caused by a trinucleotide repeat-expansion, cytosine-thymine-guanine (CTG)n, in the 3' untranslated region of DMPK . | ||
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