Recombinant Human DYRK4 (N-GST tag)
Catalog No : IGX-RP809
366.40€
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Product name | Recombinant Human DYRK4 (N-GST tag) | ||
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Catalog No | IGX-RP809 | ||
Supplier’s Catalog No | IGX-RP809 | ||
Supplier | ImuGeX | ||
Source antigen | Insect cells | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 90 |
Storage | -70°C | ||
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Other names | None | ||
Grade | Highly Purified | ||
Purity | 70% - 90% | ||
Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | 70% - 90% | ||
Description | DYRK4 or dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 plays an important role in cell proliferation, survival, and development . Northern blot analysis shows DYRK4 is highly expressed in the testis with a very restricted expression to stage VIII postmeiotic spermatids . Analysis of a DYRK4 deficient mouse line showed that DYRK4 is dispensable for male fertility, hence suggesting a functional redundancy of some DYRK isoforms during spermiogenesis. DYRK4 protein contains a DYRK homology box in its N-terminal half, followed by a central kinase domain with a YxY loop. |
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