Recombinant Human EPHB2 (611-893aa) (N-GST tag)

Catalog No : IGX-RP824
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Product name Recombinant Human EPHB2 (611-893aa) (N-GST tag)
Catalog No IGX-RP824
Supplier’s Catalog No IGX-RP824
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 56
Storage -70°C
Other names DRT, ERK, Hek5, EPHT3, Tyro5, CAPB, PCBC
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description EPHB2 is a member of the Eph family of receptor tyrosine kinases that mediate neurodevelopmental processes such as boundary formation, axon guidance, vasculogenesis, and cell migration. EPHB2 has been shown to associate with the non-receptor tyrosine kinase Abl and activated EPHB2 causes tyrosine phosphorylation of Abl and regulates its activity . EPHB2 is overexpressed in a number of tumors particularly glioblastoma and this increases glioma cell migration and invasion .