Recombinant Human ERK5 (N-GST tag)
Catalog No : IGX-RP831
366.40€
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| Product name | Recombinant Human ERK5 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP831 | ||
| Supplier’s Catalog No | IGX-RP831 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 132 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | MAPK7, BMK1, ERK4, PRKM7 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | ERK5 is a member of the MAP kinase family and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. ERK5 is activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5) and is involved in downstream signaling processes of various receptors. In response to extracelluar signals, ERK5 translocates to cell nucleus where it regulates gene expression by phosphorylating and activating different transcription factors. Gene deletion of ERK5 in mice results in defective blood vessel and cardiac development leading to embryonic lethality . ERK5 has been shown to be critical for endothelial function and maintenance of blood vessel integrity . | ||
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