Recombinant Human ERN1 (IRE1) (N-GST tag)
Catalog No : IGX-RP832
366.40€
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| Product name | Recombinant Human ERN1 (IRE1) (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP832 | ||
| Supplier’s Catalog No | IGX-RP832 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 87 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | hIRE1p; IRE1; IRE1A; IRE1P | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | ERN1 or endoplasmic reticulum to nucleus signaling 1 is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product which possesses intrinsic kinase activity and an endoribonuclease activity and it is important in endoplasmic reticulum-based stress signals. ERN1 controls IRE1 proteolysis in mammalian cells . The activation of ERN1 through oligomerization expands the mechanistic repertoire of kinase-based signaling receptors. ERNI has a critical function in extraembryonic cells that is essential for fetal viability . | ||
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