Recombinant Human FAK (N-His tag)
Catalog No : IGX-RP835
366.40€
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| Product name | Recombinant Human FAK (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP835 | ||
| Supplier’s Catalog No | IGX-RP835 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 35 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PTK2, FADK, FAK1, pp125FAK | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | FAK (Focal Adhesion Kinase ) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation . Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness . Elevated FAK expression in anaplastic astrocytoma and glioblastoma tumor biopsy samples has been demonstrated. | ||
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