Recombinant Human FMS (N-GST tag)

Catalog No : IGX-RP846
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Product name Recombinant Human FMS (N-GST tag)
Catalog No IGX-RP846
Supplier’s Catalog No IGX-RP846
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 76
Storage -70°C
Other names CSF1R, CSFR, FIM2, C-FMS, CD115
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description  FMS is a proto-oncogene that encodes the tyrosine kinase transmembrane receptor for colony stimulating factor 1 (CSF1). FMS is homodimeric that contains a so-called kinase insert domain and is a member of the CSF1/PDGF receptor family of tyrosine-protein kinases. FMS mediates most if not all of the biological effects of CSF1 which control the production, differentiation, and function of cell of the monocyte/macrophage lineage . Mutations in FMS have been associated with providing sustained signals for cell growth and a predisposition to myeloid malignancy .