Recombinant Human GCK (N-GST tag)
Catalog No : IGX-RP849
366.40€
0.00€
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| Product name | Recombinant Human GCK (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP849 | ||
| Supplier’s Catalog No | IGX-RP849 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 125 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | MAP4K2, BL44, RAB8IP | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | Â GCK is a serine/threonine protein kinase that is activated by TNFa and interacts with the TNF receptor-associated factor 2 (TRAF2). GCK is upstream of MAP kinases and particularly activates the SAPK pathway . Although GCK is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. A mouse protein Rab8ip that has high homology to GCK can interact with the vesicular transport protein Rab8. Based on its interaction with Rab8, it is postulated that Rab8ip/GCK may modulate secretion in response to stress stimuli . | ||
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