Recombinant Human GRK3 (N-GST tag)
Catalog No : IGX-RP853
366.40€
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| Product name | Recombinant Human GRK3 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP853 | ||
| Supplier’s Catalog No | IGX-RP853 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 84 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | ADRBK2; BARK2 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | GRK3 or beta-adrenergic receptor kinase 2 specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. GRK3 is a member of the receptor kinase family that broadly serves to regulate receptor function . GRK3 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. GRK3 is highly expressed in lung, heart, and adipose tissue . Single nucleotide polymorphisms (SNPs) in the promoter region of GRK3 have been associated with bipolar disorder. | ||
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