Recombinant Human GSK3 beta (N-His tag)
Catalog No : IGX-RP859
366.40€
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| Product name | Recombinant Human GSK3 beta (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP859 | ||
| Supplier’s Catalog No | IGX-RP859 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 48 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description |  GSK3ß is a serine threonine protein kinase that was originally identified as the kinase that phosphorylates and inhibits glycogen synthase . GSK3ß is ubiquitously present in human tissues and implicated in the regulation of several physiological processes, including the control of glycogen and protein synthesis by insulin, modulation of the transcription factors AP-1 and CREB. Transient transfection of human GSK3ß into Chinese hamster ovary cells stably transfected with individual human tau isoforms leads to hyperphosphorylation of tau at all the sites investigated with phosphorylation-dependent anti-tau antibodies . | ||
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