Recombinant Human HIPK3 (N-His tag)
Catalog No : IGX-RP866
366.40€
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| Product name | Recombinant Human HIPK3 (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP866 | ||
| Supplier’s Catalog No | IGX-RP866 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 49 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PKY, YAK1, DYRK6, FIST3 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | HIPK3 (homeodomain interacting protein kinase 3) is a member of the HIPK family and is involved in apoptosis . JNK regulates the expression of HIPK3 in prostate cancer cells and this contributes to increased resistance to Fas receptor-mediated apoptosis by reducing the interaction between FADD and caspase-8 . HIPK3 has been reported to phosphorylate FADD and is implicated in multidrug resistance in a number of tumors. HIPK3 increases transcription factor SF-1 activity leading to increased steroidogenic gene expression in response to cAMP signaling. | ||
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