Recombinant Human HIPK4 (N-GST tag)

Catalog No : IGX-RP867
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Product name Recombinant Human HIPK4 (N-GST tag)
Catalog No IGX-RP867
Supplier’s Catalog No IGX-RP867
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 110
Storage -70°C
Other names FLJ32818
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description HIPK4 or homeodomain interacting protein kinase 4 is a serine/threonine protein kinase that can act as a co-repressor of transcription factors . HIPK4 has been shown to phosphorylate the human p53 protein at serine 9, both in vitro and in vivo which is important for p53 mediated transcriptional repression. RT-PCR analysis showed moderate expression of HIPK4 in lung and white adipose tissue and weak expression in brain and liver. HIPK4 expression has also been observed in various cancer cell lines .