Recombinant Human IGF1R (N-His tag)
Catalog No : IGX-RP872
366.40€
0.00€
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| Product name | Recombinant Human IGF1R (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP872 | ||
| Supplier’s Catalog No | IGX-RP872 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 53 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | CD221, IGFIR, JTK13, MGC142170, MGC142172 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | IGF1R (Insulin-like Growth Factor 1) is a transmembrane tyrosine kinase receptor that is activated by IGF-1 and by the related growth factor IGF-2 . IGF1R mediates the effects of IGF-1 and plays an important role in growth and anabolic effects in adults. The IGF1R is implicated in several cancers, most notably breast cancer where it is highly overexpressed and functions as an anti-apoptotic agent by enhancing cell survival. In many instances, the anti-apoptotic properties of IGF1R overexpression allows cancerous cells to resist the cytotoxic properties of chemotheraputic drugs or radiotherapy . | ||
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