Recombinant Human JNK3 (N-GST tag)
Catalog No : IGX-RP886
366.40€
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| Product name | Recombinant Human JNK3 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP886 | ||
| Supplier’s Catalog No | IGX-RP886 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 71 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | MAPK10; JNK3A, MGC50974, PRKM10, p493F12, p54bSAPK; FLJ12099, FLJ33785 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | JNK3 is a member of the c-Jun N-terminal kinases (JNKs) which are part of the mitogen-activated protein (MAP) kinase family, and regulate signal transduction in response to environmental stress. JNK3 phosphorylates various transcription factors such as ATF2, Elk-1 and members of the Jun family . Activation and nuclear localization of JNK3, a neuronal-specific isoform of JNK, has been associated with hypoxic and ischemic damage of CA1 neurons in the hippocampus. Knockout mice lacking JNK3 showed reduced apoptosis of hippocampal neurons and reduced seizure induced by kainic acid, a glutamate-receptor agonist . | ||
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