Recombinant Human KSR2 (N-GST tag)

Catalog No : IGX-RP891
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Product name Recombinant Human KSR2 (N-GST tag)
Catalog No IGX-RP891
Supplier’s Catalog No IGX-RP891
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 72
Storage -70°C
Other names none
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description KSR2 or kinase suppressor of Ras 2 specifically regulates the activity of MEKK3 and COT but not other members of the MAP3K family . KSR interacts with a regulatory Raf molecule in cis to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf molecule in trans .