Recombinant Human LATS2 (N-GST tag)

Catalog No : IGX-RP893
366.40€
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Product name Recombinant Human LATS2 (N-GST tag)
Catalog No IGX-RP893
Supplier’s Catalog No IGX-RP893
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 110
Storage -70°C
Other names none
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description  LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. LATS2 interacts with a negative regulator of p53 and function in a positive feedback loop with p53 that responds to cytoskeleton damage and this interaction provokes centrosome/mitotic apparatus dysfunction . LATS2 plays an essential role in the maintenance of mitotic fidelity and genomic integrity .