Recombinant Human LYN A (N-GST tag)
Catalog No : IGX-RP899
366.40€
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| Product name | Recombinant Human LYN A (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP899 | ||
| Supplier’s Catalog No | IGX-RP899 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 81 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | JTK8, FLJ26625 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | LYN A is a member of the Src-family of protein kinases that participate in signaling pathways of a variety of cell surface receptors and are localized to the cytoplasmic side of the plasma membrane . LYN A is biosynthetically transported to the plasma membrane via the Golgi pool of caveolin along the secretory pathway. The trafficking of LYN A from the Golgi apparatus to the plasma membrane is inhibited by deletion of the kinase domain but not by kinase inactivation. The kinase domain of LYN A plays a role in LYN A trafficking besides catalysis of substrate phosphorylation. cDNA microarray analysis revealed that LYN A may be involved in the changes that are related to tumor pathogenesis . | ||
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