Recombinant Human MATK (CTK) (N-GST tag)

Catalog No : IGX-RP910
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Product name Recombinant Human MATK (CTK) (N-GST tag)
Catalog No IGX-RP910
Supplier’s Catalog No IGX-RP910
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 83
Storage -70°C
Other names CHK; CTK; HHYLTK; HYL; HYLTK; LSK
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description MATK belongs to tyrosine protein kinase family, CSK subfamily. It inactivates Src family kinase activity by specifically phosphorylating their C-terminal regulatory tyrosine residue and may plays a significant role in the signal transduction of hematopoietic cells . MATK binds to the phosphorylated Tyr568/570 sites on c-KIT to which FYN binds and leads to the down-regulation of FYN . MATK has been shown to be involved in signaling in some cases of breast cancer.