Recombinant Human MATK (CTK) (N-GST tag)
Catalog No : IGX-RP910
366.40€
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Product name | Recombinant Human MATK (CTK) (N-GST tag) | ||
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Catalog No | IGX-RP910 | ||
Supplier’s Catalog No | IGX-RP910 | ||
Supplier | ImuGeX | ||
Source antigen | Insect cells | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 83 |
Storage | -70°C | ||
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Other names | CHK; CTK; HHYLTK; HYL; HYLTK; LSK | ||
Grade | Highly Purified | ||
Purity | 70% - 90% | ||
Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | 70% - 90% | ||
Description | MATK belongs to tyrosine protein kinase family, CSK subfamily. It inactivates Src family kinase activity by specifically phosphorylating their C-terminal regulatory tyrosine residue and may plays a significant role in the signal transduction of hematopoietic cells . MATK binds to the phosphorylated Tyr568/570 sites on c-KIT to which FYN binds and leads to the down-regulation of FYN . MATK has been shown to be involved in signaling in some cases of breast cancer. |
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