Recombinant Human MEK5 (N-GST tag)
Catalog No : IGX-RP913
366.40€
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| Product name | Recombinant Human MEK5 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP913 | ||
| Supplier’s Catalog No | IGX-RP913 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 77 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | MAP2K5, MAPKK5, MKK5, PRKMK5, SAPKK5; SKK5; HsT17454 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | MEK5 or MAP2K5 (mitogen-activated protein kinase kinase 5) is a dual specificity protein kinase that belongs to the MAP kinase kinase family which specifically interacts with and activates MAPK7/ERK5. MEK5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MEK5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation . The rs3743354 polymorphism in the MEK5 promoter may affect the risk of developing colorectal cancer (CRC) . | ||
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