Recombinant Human MEKK6 (N-GST tag)
Catalog No : IGX-RP918
366.40€
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| Product name | Recombinant Human MEKK6 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP918 | ||
| Supplier’s Catalog No | IGX-RP918 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 67 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | MAP3K6, MAPKKK6, ASK2 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | MEKK6 or MAP3K6 (mitogen-activated protein kinase kinase kinase 6) is a member of the serine/threonine protein kinase family. MEKK6 was identified by its interaction with MAP3K5/ASK, a protein kinase and an activator of c-Jun kinase (MAPK7/JNK) and MAPK14/p38 kinase . MEKK6 cascades relay signals from the cell surface to the nucleus which result in gene transcription . MEKK6 activates the JNK and p38 pathway and induces apoptosis when overexpressed in stably transfected cells. MEKK6 transcript is expressed in several tissues, with the highest expression in heart and skeletal muscle. | ||
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