Recombinant Human MINK1 (N-GST tag)
Catalog No : IGX-RP922
366.40€
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| Product name | Recombinant Human MINK1 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP922 | ||
| Supplier’s Catalog No | IGX-RP922 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 61 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | B55; ZC3; MINK; YSK2; hMINK; MAP4K6; MGC21111; hMINKß | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | MINK1 is a member of the germinal center family of kinases that are homologous to the Ste20 family and regulate a wide variety of cellular processes, including cell morphology, cytoskeletal rearrangement, and survival . Overexpression of kinase-dead mutants of MINK1 leads to enhanced cell spreading, actin stress fiber formation, adhesion to extracellular matrix and decreased cell motility and invasion. MINK is activated after Ras induction via a mechanism involving reactive oxygen species and mediates stimulation of p38 MAPK downstream of the Raf/ERK pathway . | ||
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