Recombinant Human MUSK (N-GST tag)
Catalog No : IGX-RP937
366.40€
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| Product name | Recombinant Human MUSK (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP937 | ||
| Supplier’s Catalog No | IGX-RP937 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 63 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | MGC126323, MGC126324 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | MUSK is a receptor tyrosine kinase necessary for neuromuscular junction formation . MUSK gene expression is highly regulated during neuromuscular junction and it is involved in intercellular communication present on the surface of cells that are activated by specific protein ligands. MUSK members play a key role in growth and differentiation of those cell types. Agrin signals through MUSK to cluster acetylcholine receptors on the postsynaptic membrane of the neuromuscular junction. DOK7, a MUSK-interacting cytoplasmic protein, is essential for MUSK activation in cultured myotubes. MUSK also plays a critical role in the development of normal blood vessels . | ||
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