Recombinant Human MYO3alpha (N-GST tag)

Catalog No : IGX-RP942
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Product name Recombinant Human MYO3alpha (N-GST tag)
Catalog No IGX-RP942
Supplier’s Catalog No IGX-RP942
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 76
Storage -70°C
Other names myosin IIIA; DFNB30
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description MYO3alpha belongs to the myosin superfamily which are members of the large myosin superfamily and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3alpha, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors . MYO3alpha plays an important role in hearing in humans and mutations in the MYO3alpha have been shown to cause nonsyndromic progressive hearing loss . MYO3alpha is highly expreesed in retina and cochlea.