Recombinant Human NEK5 (N-GST tag)

Catalog No : IGX-RP949
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Product name Recombinant Human NEK5 (N-GST tag)
Catalog No IGX-RP949
Supplier’s Catalog No IGX-RP949
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 84
Storage -70°C
Other names MGC75495
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description NEK5 or NIMA (never in mitosis gene a)-related kinase 5 is a serine/threonine kinase that is involved in cell cycle regulation. NEK5 has been shown to interact with NEK6 and NEK5 are required for the ibo1/nek6 ectopic outgrowth phenotype in epidermal cells . NEK6 interacts and co-localizes with NEK5 in a transient expression assay. The ibo1-3 mutation markedly increases the interaction between NEK6 and NEK5. NEK6 forms heterodimers with NEK5 to regulate cortical microtubule organization possibly through the phosphorylation of ß-tubulins. The NEK5 gene is conserved in chimpanzee, cow, mouse, rat, and chicken.