Recombinant Human NLK (N-GST tag)
Catalog No : IGX-RP956
366.40€
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| Product name | Recombinant Human NLK (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP956 | ||
| Supplier’s Catalog No | IGX-RP956 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 84 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | FLJ21033, DKFZp761G1211 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | NLK (also known as nemo-like kinase) is a member of the serine/threonine protein kinase that is encoded by the NLK gene. NLK plays a role in cell fate determination and is required for the differentiation of bone marrow stromal cells. NLK also suppresses a wide range of transcription factors such as CREB by phosphorylation of the co-activator CREBBP. NLK expression increases the number of apoptotic cells but does not induce obvious cell cycle arrest . NLK suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex . | ||
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