Recombinant Human PCTK3 (CDK18)/CyclinY (N-GST tag)

Catalog No : IGX-RP973
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Product name Recombinant Human PCTK3 (CDK18)/CyclinY (N-GST tag)
Catalog No IGX-RP973
Supplier’s Catalog No IGX-RP973
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 76
Storage -70°C
Other names PCTK3: PCTAIRE, PCTAIRE3 CyclinY: CCNY; C10orf9; CBCP1; CCNX; CFP1
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, , pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description PCTK3 or PCTAIRE protein kinase 3 is a member of the cdc2/cdkx subfamily of the ser/thr family of protein kinases. PCTK3 is thought to play a role in terminally differentiated neurons and it contains an N-terminal extension relative to CDC2 . PCTK3 is expressed in a variety of human cell lines and tissues . Elevation in the protein levels of PCTAIRE 3 in the temporal cortex of Alzheimer's disease relative to control brains, have been observed. It is proposed that PCTAIRE 3 is a paired helical filaments-associated kinase that modulates tau phosphorylation.